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FOREWORD
Dear reader,
this book contains a number of papers which were presented in talks or on
posters during the 5th Symposium of the International Cartilage Repair
Society (Gent, Belgium, May 26-29, 2004). The authors did and still do
significantly contribute to a young discipline’s development, and it is a
central mission of the ICRS to foster the exchange of knowledge in the field
of cartilage repair. I am sure this book will serve as an additional
platform to serve this purpose.
On behalf of the ICRS I wish you interesting and enlightening moments – and,
last but not least, pleasure – while reading this book.
Alexander Konstantinidis, MD
ICRS Executive Director
INDEX
Keynote
Lecture
Biomaterials in Cartilage Tissue Engineering: Needed or Not?
G.J.V.M. van Osch and H. Weinans
State of the Art
Meniscus Repair: Clinical Studies
K. DeHaven
Systemic Chondroprotection
P. Ghosh
Biology of Articular Cartilage
G. Verbruggen, J. Wang, D. Elewaut and EM. Veys
Basic Science
Self-Assembling Peptide Nanomaterials as Injectable Lubricants for
Osteoarthritis
C.J. Bell, L.M. Carrick, E. Ingham, A. Aggeli, N. Boden, T.A. Waigh and J.
Fisher
Visco-elastic Model Extraction of a Cartilage Under Periodic Loading
P. Saraswat and J.K. Dutt
Tracing of Transplanted Chondrocytes by Fluorescent Labeling with PKH67
M. Gorensek, M. Froelich, N. Mohorko, B. Gorensek, N. Kregar-Velikonja, A.
Cör and M. Bresjanac
Long Term Evaluation of the Synthetic Thrombin Peptide, TP-508 in a model of
Articular Cartilage Repair Using a New Delivery System
D. Grande, J. Lessmann, P. Razzano, D. Carney, R. Crowther and J. Ryaby
Photocrosslinkable Biodendrimer-based Hydrogel Scaffolds for Cartilage
Tissue Repair
S.H.M. Söntjens, D.L. Nettles, M.A. Carnahan, L.A. Setton and M.W. Grinstaff
Autologous Chondrocyte Implantation Using a Microsurgical Technique for
Suturing the Periosteal Flap. Results at 18 Months
J.H.P. Hui, J.K. Lim, A.Y.T. Lim, K.P. Looi and E.H. Lee
Spontaneous Healing of Partial Thickness Cartilage Defects in the Stifle
Joint of the Sheep
A. Jubel, A. Gossmann, H. Bergmann, J.H. Fischer, M. Bosse, J. Andermahr, J.
Koebke, E. Hedbom, K.E. Rehm and H.J. Häuselmann
Functional Improvement of Full Thickness Cartilage Injuries In Goats Treated
With a Resorbable Chondroconductive Implant
T. Kapur, D. Grande, J. Orban, R. Steckel , P. Plouhar, J. Hammer, M. O’Connell
and H. Schwartz
Assessment of Cartilage Formation and Immunogenicity of Progenitor Cells in
an Allogeneic Rabbit Focal Defect Study
D. Kidd, R. Turner, S. Boyer, J. Dodd and C. Booth
AG-041R, a Novel Indoline-2-one Derivative, Stimulates Chondrogenesis In
Vitro and In Vivo
H. Kitamura, M. Okazaki, Y. Higuchi, M. Tanaka, A. Kato, T. Esaki, S. Nagao,
Y. Hayashi and F. Makishima
Changes After Meniscectomy? Yes, They Start Early!
E. Lindhorst, N. Kimmig, J. Warzecha, F. Hentschel, R. Raiss, T. Aigner and
L. Wachsmuth
Modulation of Pro-inflammatory Mediator and Metalloproteinase Expression in
Human Synoviocytes
L. Lindmark, A. Sohrabi, P.V. Phan, A.S. Polotsky, M.O. Overstreet, D.S.
Hungerford and C.G. Frondoza
Integration of Engineered Cartilage Matrix to Live and Devitalized Cartilage:
A Morphological Study by Confocal and Light Microscope
G.M. Peretti, V. Campo-Ruiz, J.W. Xu, M.A. Randolph, K.R. Morse, R.E. Roses,
S. Gonzalez, G. Fraschini and M.J. Yaremchuk
Comparison Between the Prophylactic Chondroprotective Power of Diacerhein,
Glucosamine and Glucosamine-Chondroitin
M.U. Rezende, A.S.S. Lopes, C.R.G.C.M. Oliveira, R. Bolliger Nt., M.M.
Amatuzzi and A.J. Hernandez
Clinical
Accuracy and Reliability of Arthroscopic Assessments of Chondral Defects in
Cadaveric Knee Specimens
M. Wilson, S. Nash-Scholl, J.P. Albright, K. Spratt, M. Wolcott and A.
Amendola
Tissue Engineering Cartilage in the Treatment of Traumatic Chondral Defects
of Patella Femoral Joint
S. Odella, E. Paresce, M. Berruto, A. Murgo, E. Uderzo and F. Fantini
Implantation of Autologous Chondrocytes in a 3-D Resorbable Polymer Fleece
for the Treatment of Cartilage Defects in the Knee Joint
C. Erggelet, A. Dauch, A. Lahm, P. Kreuz, C. Ossendorf, E. Mrosek and M.
Sittinger
Treatment of Cartilaginous Defects of the Knee with an Osteochondral
Autogenous Graft from the Upper Tibio-Peroneal Joint - GUT
J. Espregueira-Mendes, A. Monteiro, P. Amado, M. Mendonça and M. Vieira da
Silva
Cartilage Reconstruction by Tissue Engineering After Nasal Septum Abscess in
Children
M. Fussenegger, G. Oberascher, S. Wieser, T. Muhr, L. Dinkhauser and J.
Meinhart
Arthroscopic Treatment of Osteochondral Lesions of the Talus: A Prospective
Study of Three Different Techniques
A. Gobbi, F. Allegra, G. Canata, R. Francisco and M. Vitali
Clinical Results in Patellofemoral Full Thickness Chondral Defects Treated
with Hyalograft®-C: A Prospective Study at 2-years Follow-up
A. Gobbi, M. Berruto, R. Francisco and M. Vitali
Autologous Chondrocyte Implantation for Treatment of Focal Chondral Defects
of the Knee
I. Henderson, R. Francisco, B. Oakes and J. Cameron
The Efficacy of Intra-articular Injection of Chondroitin Sulfate in
Prevention of Osteoarthritis in Rabbits
L. Li, J.H.P. Hui, J. Li, X. Wang and E.H. Lee
Cartilage Engineering with Hyalograft® C: 20-Month Clinical Results
E. Kon, M. Marcacci and the
Hyalograft® C Clinical Study Group
Arthroscopic Autologous Chondrocyte Transplantation. Prospective Study:
Results at 1 and 2 Years Follow-up
M. Marcacci, E. Kon, S. Zaffagnini, L. Marchesini Reggiani, F. Iacono and
M.P. Neri
Tissue Engineering in the Treatment of Osteochondritis Dissecans
M. Marcacci, M. Berruto, E. Kon, S. Zaffagnini, L. Marchesini Reggiani, M.P.
Neri and S. Odella
Delayed Gadolinium Enhanced MRI of Cartilage (dGEMRIC) Evaluation Compared
with Clinical and Functional Outcomes in Three Different A.C.I. Procedures:
A Three Year Follow-up Study
E. Marinoni, M. Berruto, E. Colombo, E. Uderzo, S. Odella, G.P. Carrafiello,
D. Capitani and A. Vanzulli
Hyaluronic Acid for the Treatment of Knee Osteoarthritis: Long Term Outcomes
from a Naturalistic Practice Experience
R. Petrella
Clinical Results and MRI Findings After Collagen Meniscus Implant (CMI)
M. Ronga, F. Grassi, P. Bulgheroni, E. Genovese and P. Cherubino
Arthroscopic Autologous Chondrocyte Implantation: Mid-term Results
A. Scorrano and F. Biggi
The Relationship Between the In Vivo Measured Stiffness and the Histological
Stage of Degeneration of Human Knee Articular Cartilage
I. Szerb
Tissue Engineered Cartilage Approach with Hyalograft® C in Complex and
Salvage Procedures Associated with Unloading Osteotomy
S. Zanasi
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